Professor Nigel Slater
BA, MA, PhD, FREng, CEng, FIChemE
Fellow
Subject: Chemical Engineering
Department: Chem. Eng. and Biotechnology
Role:
JMA Senior President
President
Safety Officer
Email: nkhs2@cam.ac.uk
Phone: (+44 1223 7) 68488
Profile
Nigel is Head of the Department of Chemical Engineering and Biotechnology at Cambridge, where he holds the Chair of Chemical Engineering 1999.
Nigel obtained BA and PhD degrees in Natural Sciences whilst a student at Sidney Sussex College and was a Research Fellow in Chemistry at Fitzwilliam College in 1978. He became a University Assistant Lecturer in Chemical Engineering in 1979.
Nigel left academia in 1985 to lead the Bioprocessing Section at Unilever's research laboratories in the Netherlands and in 1990 he joined Wellcome Biotech to lead the process design for their WelGen (later BWMI) interferon manufacturing plant in Rhode Island (US). He was a co-founder of Cobra BioManufacturing plc and Angel Technology Ltd, which was awarded the Queen's Award for Innovation in 2006.
Nigel was appointed to a Professorial Fellowship upon returning to Cambridge in 2000 and became President of Fitzwilliam College in 2009.
Teaching:
Nigel teaches bioprocess engineering ranging from introductory material on microbial heat and mass balances and growth kinetics (Part I), though bioreactor design and downstream processing (IIA), to the complex regulatory requirements for the manufacture of biological drugs (IIB).
Research interests:
Biopharmaceuticals; drug targeting; bionanotechnology.
Selected recent publications:
Darton, N.J., Reis, N.M., Mackley M.R. and N.K.H. Slater (2011). Fast cation-exchange separation of proteins in a plastic microcapillary disc. J. Chromatog. A. 1218(10), 1409-1415.
Ho, V.H.B., N.K.H. Slater and R. Chen (2011). pH-responsive endosomolytic pseudo-peptides for drug delivery to multicellular spheroids tumour models. Biomaterials32, 2953-2958.
Ho, V.H.B., Smith, M.J. and N.K.H. Slater (2011). Effect of magnetite nanoparticle agglomerates on the destruction of tumor spheroids using high intensity focused ultrasound. Ultrasound in Med. & Biol.37(1), 169-175.
Lynch, A.L., Chen, R. and N.K.H. Slater (2011). pH-Responsive polymers for trehalose loading and desiccation protection of human red blood cells. Biomaterials32, 4443-4449.
Lynch, A.L. and N.K.H. Slater (2011). Influence of intracellular trehalose concentration and pre-freeze cell volume on the cryosurvival of rapidly frozen human erythrocytes. Cryobiology (doi: 10.1016/j.cryobiol.2011.04.005).