Dr Kourosh Saeb-Parsy

Dr Kourosh Saeb-Parsy

MA, MB BChir, PhD, FRCS

Fellow

Subject: Medical Sciences
Department: Transplant Unit

Role:
Director of Studies, Clinical Medicine

Email: ks10014@cam.ac.uk
Phone: (+44 1223 7) 68456

Profile

I am a Clinical Lecturer at the Department of Surgery, University of Cambridge, and an Honorary Specialist Registrar in Transplant Surgery at Addenbrooke's Hospital, Cambridge. My clinical interests include adult liver, kidney, pancreas and small bowel transplantation. I additionally conduct post-doctoral scientific research in Transplant Immunology focused on mechanisms of organ rejection. I am a College Lecturer at Fitzwilliam where I teach Mechanisms of Drug Action (pharmacology) to second year undergraduate medical and veterinary students. As the Director of Studies in Clinical Medicine, I am responsible for the academic progress of clinical medical students at Fitzwilliam College. Together with other medical and veterinary fellows, I am involved in the admissions process and interview applicants that wish to read Medical and Veterinary Sciences Tripos at Fitzwilliam College, University of Cambridge.

Background 

I matriculated as a medical student at Fitzwilliam College in 1993. My interest in biomedical research was developed during my Part II year studying Anatomy A (neurosciences and developmental biology) and I subsequently enrolled on the MB-PhD programme. I completed my doctoral thesis in neurophysiology of circadian rhythms in 2000 and qualified as a medical doctor in 2001.  While studying for my PhD, I pursued an active interest in teaching and supervised undergraduates at Fitzwilliam and several other colleges. I served as MCR President in 1999. I was appointed as a Fellow at Fitzwilliam College in 2003 and as the Director of Studies in Clinical Medicine in 2004. I pursued a career in surgery after graduation and was appointed as a Clinical Lecturer at the University Department of Surgery in 2007, sub-specialising in academic multivisceral (abdominal) transplantation.

Teaching interests:

  • MVST IB Mechanisms of Drug Action (pharmacology) - Fitzwilliam College
  • Surgery to clinical medical students and surgeons in training - Addenbrooke's Hospital

Research interests:

  • Mechanisms of CD8 T cell-mediated and antibody-mediated alloimmune response
  • Longevity of the 'direct' and 'indirect' alloimmune response
  • Memory CD4 and CD8 T cell responses to alloantigens

    Selected recent publications:

    1) Saeb-Parsy K, Kosmoliaptsis V, Sharples LD, Watson CJ, Clatworthy MR, Taylor CJ, Pettigrew GJ, Bradley JA (2010) Donor Type Does Not Influence the Incidence of Major Urologic Complications After Kidney Transplantation. Transplantation 90, 1085-90.

    2) Saeb-Parsy K, Mills A, Rang C, Reed JB, Harris AM (2010). Emergency laparoscopic cholecystectomy in an unselected cohort: A safe and viable option in a specialist centre. International Journal of Surgery 8, 489-93.

    3) Bhumbra GS, Lombardelli S, Gonzalez JA, Saeb-Parsy K and Dyball REJ (2009). Daily Rhythms of Spike Coding in the Rat Supraoptic Nucleus. Journal of Neuroendocrinology 21, 935-945.

    4) Win TS, Rehakova S, Negus M, Saeb-Parsy K, Goddard M, Conlon M, Bolton EM, Bradley JA & Pettigrew GJ (2009) Donor CD4 T cells contribute to cardiac allograft vasculopathy by providing help for autoantibody production. Circulation: Heart Failure 2, 361-9.

    5) Saeb-Parsy K, Jah A, Butler AJ, Large S, Pettigrew GJ, Praseedom RK, Watson CJ & Jamieson NV (2009) Use of a donor aortic interposition allograft to treat stenosis of the suprahepatic inferior vena cava after liver transplantation. Liver Transplantation 15, 662-5.

    6) Saeb-Parsy K, Bolton EM (2009) Antiplatelet Therapy in Transplantation: New Tricks from Old Drugs? Transplantation 87, 633-5.

    7) Saeb-Parsy K, Bradley JA & Jamieson NV (2008) Small bowel transplantation in adults. UK Transplant Bulletin 65, 12-13.

    8) Saeb-Pary K, Watson CJ & Bradley JA (2007) Organ preservation in renal transplantation. British Journal of Renal Medicine 12, 4 (suppl.) 1-6.

    9) Drain AJ, Saeb-Parsy K, Shah AK & Rassl D and AJ Ritchie (2006) Mesothelioma with non-pleural malignancy: a red herring or just an uncommon pairing? Journal of Cardiothoracic Surgery 1, 39.

    10) Saeb-Parsy K, Athanassoglou V & JR Benson (2006) Talc seromadesis: A novel technique for the treatment of chronic seromas following breast surgery. Breast Journal 12, 502-4.

    11) Benson JR, Saeb-Parsy K (2006) Meta-analyses in cancer clinical trials: principles and pitfalls. World Journal of Surgery 30, 1177-83.

    12) Saeb-Parsy K, Omer A, Hall NR (2006) Melaena as the presenting symptom of gastric mucosal injury due to blunt abdominal trauma. Emergency Medicine Journal 23, 34.

    Instant Pharmacology. Saeb-Parsy K, Assomull RG, Kelly E, Khan FZ & Saeb-Parsy K. John Wiley & Sons Ltd, 1999, 368 pp, ISBN: 0471976393.